Outline
- The Priapus Toxin™ and P-Shot 100™ procedures
- Scientific research regarding Priapus Toxin™ and P-Shot 100™
- How to schedule an appointment
The Priapus Toxin™ and P-Shot 100™ Procedures
We have now been doing the P-Shot® procedure for over ten years with much success and with a significant body of medical research supporting the procedure.
Over the past six years, a growing body of research (in animals and people) also supports the effectiveness and safety of injecting the corpus cavernosi of the penis with BOTOX. In the latest randomized, double-blind, placebo-controlled prospective comparative study, the most effective and longest-lasting dose for improvement of erection firmness was 100 units of BOTOX, in total (50 units into each corpus cavernosi). This dose showed effectiveness up to 6 months with maximal effect at 6 weeks.
The mechanism of action of botulinum toxin in the penis seems to be partly due to the relaxation of the smooth muscle of the arterioles, resulting in increased blood flow (and even a small increase in length in one study). This increase in erection firmness by increasing arterial flow is exactly how Viagra and Tri-mix injections work. In two separate studies, the injection of botulinum toxin was helpful to some men (not all) for whom Viagra and Cialis had quit working.
Botulinum toxin (at doses much higher than 100 units) has been used for two decades for various problems with an extremely safe history.
The P-Shot 100™ (Priapus Toxin™) procedure is a specific method of injecting blood-derived growth factors, including platelet-rich plasma (or platelet-rich fibrin matrix) and botulinum neurotoxin, to improve the health of the penis and enhance the size or function of the penis. The procedure includes patient selection, method of preparation of materials, method of injection, aftercare, and more.
I am now offering the P-Shot® (Priapus Shot®) procedure combined with 100 units of Botox–the combination of the two is called the P-Shot 100™ (Priapus Toxin™) procedure.
Suppose someone wants Botox alone injected into the penis. In that case, we have the Priapus Toxin™ procedure: a specific method of injecting the corpus cavernosi of the penis with botulinum neurotoxin (BoNT)–BOTOX– to improve penile tissue health and to enhance erectile function or penis size. The procedure includes patient selection, the method of preparation of the botulinum toxin, the method of injection of the botulinum toxin, aftercare, and more.
As with all procedures, there can be no guarantee of the outcome (though I do guarantee not to keep your money if the procedure does not meet your expectations), and there can be complications (some unexpected and of unknown severity). Using Botox for ED is an off-label use for BOTOX not approved by the FDA--as are other common "off-label" uses of BOTOX. Some experts do not think Botox should be used for ED. Thankfully, we have 2 decades of use of Botox, with millions of doses per year, for many indications with an extremely high safety profile. The toxic LD50 for injecting cosmetic Botox iv for a 180-pound man is estimated to be around 150 to 200 Bottles of Botox (or around 15,000 to 20,000 units); we only inject a total of 100 units of Botox (one bottle) into the corpus carvernosi when we do the procedure (a smaller dose than what is often used to treat children with muscle spasm).
Guarantee: If you are not pleased with the results of your procedure for any reason or no reason at all, you can get a full refund for the procedure for up to 6 months.
Scientific Research
- Abdelrahman, Islam Fathy Soliman, Amr Abdel Raheem, Yaser Elkhiat, Abdelrahman A. Aburahma, Tarek Abdel-Raheem, and Hussein Ghanem. “Safety and Efficacy of Botulinum Neurotoxin in the Treatment of Erectile Dysfunction Refractory to Phosphodiesterase Inhibitors: Results of a Randomized Controlled Trial.” Andrology 10, no. 2 (2022): 254–61. https://doi.org/10.1111/andr.13104.
- El-Shaer, Waleed, Hussein Ghanem, Tamer Diab, Ahmed Abo-Taleb, and Wael Kandeel. “Intra-Cavernous Injection of BOTOX® (50 and 100 Units) for Treatment of Vasculogenic Erectile Dysfunction: Randomized Controlled Trial.” Andrology 9, no. 4 (2021): 1166–75. https://doi.org/10.1111/andr.13010.
- Giuliano, Francois, Charles Joussain, and Pierre Denys. “Safety and Efficacy of Intracavernosal Injections of AbobotulinumtoxinA (Dysport®) as Add-on Therapy to Phosphosdiesterase Type 5 Inhibitors or Prostaglandin E1 for Erectile Dysfunction—Case Studies.” Toxins 11, no. 5 (May 21, 2019): 283. https://doi.org/10.3390/toxins11050283.
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Habashy, Engy, and Tobias S. Köhler. “Botox for Erectile Dysfunction.” The Journal of Sexual Medicine 19, no. 7 (July 2022): 1061–63. https://doi.org/10.1016/j.jsxm.2022.03.216.
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Naumann, Markus, and Joseph Jankovic. “Safety of Botulinum Toxin Type A: A Systematic Review and Meta-Analysis.” Current Medical Research and Opinion 20, no. 7 (July 2004): 981–90. https://doi.org/10.1185/030079904125003962.
How to Schedule an Appointment
If I speak with you by phone after you schedule your appointment or even during your initial visit, and we determine the procedure may not be the best choice for you, then you will receive a complete and cheerful refund. You will not even be charged for the consultation.
— Charles Runels, MDP-Shot 100™ (Priapus Toxin™)
The P-Shot® procedure combined with the Bocox™ procedure (PRP combined with 100 Units of BOTOX).
$2,787
Schedule here<–Priapus Toxin™ Procedure: botulinum toxin 100 units alone (no P-Shot® added) injected into the penis (50 units into each corpus cavernosum)
$1,797
Schedule here<–
P-Shot® (Priapus Shot®) Procedure: The first procedure.
$1,800
Schedule here<–
Repeat P-Shot® (Priapus Shot®) Procedure: Repeat injection (recommended to wait 8-12 weeks for the full benefit of the first injection before determining if a second injection is needed)
$997
Schedule here<–
I have had 3 P-shots each one lasted about 5-6 months, 15 gainswave tx during those times and one before each one. 2 shots with just exosomes , that made no difference at all, a real waste of money. The last time was a 1 p-shot with exosomes that lasted the longest 9 months. I can easily get an erection, but have a hard time to maintain it unless I use a penis ring. I also am taking 100 mg of Cialis to accomplish this. Do you think the BoNT will be any better ? Should I have the P-shot with exosomes and the BoNT all together. I really am just looking for a solution . I am 70 years old and have an enlarged prostate so I also take 5mg of cialis daily. I also take weekly Testosterone injections.
In the studies done thus far, the people treated were men who had quit responding to Viagra/Cialis at all–so they were difficult to treat, and still, the treatment worked better than the placebo. But, not all of them got better. As with any treatment, it’s usually impossible to know for sure who will respond and who will not. Our P-Shot® and P-Shot 100™ and Bocox™ providers should be offering a money-back guarantee. Just ask your provider if they offer that. If they do not, use a different person. Exosomes are probably helpful but are not approved by the FDA in the US. There was a time the FDA was giving a grace period, but they have started enforcing this now, so I really don’t want to comment further about exosomes (I do not offer them in my office).
Doc, Roy Swindal. What do you think about this. It sounds great
Dear Sir,
do you think that P.shot can be extended to the area of the prostate (P spot) with efficacity and sécurity?
all my very best